Joined: 09/24/2012
Groups: Go Science
Same objectives as before

Objectives
Residue Count (max +550)
Penalizes extra residues inserted beyond the starting 192, at a cost of 55 points per residue. Players may use up to 202 residues in total.

Core Existence (max +2400)
Ensures that at least 28 percent of residues are buried in the core of the monomer unit.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.

The total maximum bonus is 3950

LociOiling's picture
User offline. Last seen 1 hour 36 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders
typo patrol

The line:

a new highly-infections virus

should read:

a new, highly infectious virus

I considered a second comma in there, but decided against it.

Joined: 03/04/2020
Groups: None
hello im an artist and I understand hlab27 gene has some immunit

is that your covirus protein? you have lots of sheets !
so the new challenge is to design a protien that will bind to the human site ?

Joined: 09/24/2012
Groups: Go Science
wizardosro

The challenge is to design a protein that will bond to the virus site (so that it cannot bind to the human site)

LociOiling's picture
User offline. Last seen 1 hour 36 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders
evolver play a problem

This puzzle lets you continue work on your 1805b results, but evolver mode is a problem, since solutions load with much lower score, but evolving them still requires adding two points to the 1850b score.

For example, my 1805b solution scoring 16,534 loaded at 15,704 in 1808. But it still wants 16,536 to evo. I saw similar results in other solutions. I'm guessing that most of the evolvers are working on new solutions.

Joined: 03/11/2020
Groups: None
We Must Solve this CoronaVirus

This Coronavirus is a killer. I send my prayers to the families of the dead to this horrible disease. If one of us could crack this case, lives would be saved. As a society we must solve this. Please help everyone this needs to be solved. Nobody else should die.

jeff101's picture
User offline. Last seen 2 hours 23 min ago. Offline
Joined: 04/20/2012
Groups: Go Science
Can players load Beginner Coronavirus Puzzle solutions here?

Can players load their solutions
from the Beginner Coronavirus Puzzle
(https://fold.it/portal/node/2008951)
into this one?

bkoep's picture
User offline. Last seen 2 hours 26 min ago. Offline
Joined: 11/15/2012
Groups: None
No loading from Beginner Puzzle

No, solutions from the Beginner puzzle are incompatible with this puzzle. Players may not load solutions from the Beginner puzzle.

Download links:
  Windows    OSX    Linux  
Windows
(7/8/10)
OSX
(10.12 or later)
Linux
(64-bit)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Search
Only search fold.it
Other Games: Mozak
Recommend Foldit
User login
Topics
Top New Users
Sitemap

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons