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1775: Poly-Proline Helix Design: Round 4
Status: Closed


Name: 1775: Poly-Proline Helix Design: Round 4
Status: Closed
Created: 12/19/2019
Points: 100
Expired: 12/26/2019 - 23:00
Difficulty: Intermediate
Description: This is the fourth puzzle in the poly-proline helix design series! The starting structure is identical to the one in round 3, with an 80 residue protein and an 8 residue helix. The backbone will be frozen to maintain the poly-proline helix secondary structure, but we are now giving you free rein to design the residues on the helix. We want to see how you will satisfy the exposed oxygens on the helix backbone, because proteins that satisfy all internal oxygens with hydrogen bonds have the best chance of folding in the lab. Happy folding!
Categories: Design, Overall

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neilpg628's picture
User offline. Last seen 9 weeks 4 days ago. Offline
Joined: 08/01/2019
Groups: Foldit Staff

Residue Count (max +100)
Penalizes a residue count above 80 by 20 Foldit points per additional residue. The count is capped at 85.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons