1772: Poly-Proline Helix Design: Round 3
|Name:||1772: Poly-Proline Helix Design: Round 3|
|Expired:||12/19/2019 - 23:00|
|Description:||This is the third puzzle in our poly-proline helix design series! This is an 80 residue protein with a shorter 8-residue long frozen poly-proline helix, and designable residues on either side. Just like in Rounds 1 and 2, it will be necessary to satisfy the exposed oxygens on the helix backbone to ensure that the protein stays folded! Globular structures with a hydrophobic core will have the best chance of folding in the real world.
In addition we have upweighted the scores of any interactions with the proline residues by a factor of 5, to incentivize satisfying and bonding with the poly-proline helix.
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