puzzle picture
1769: Poly-Proline Helix Design: Round 2
Status: Closed


Name: 1769: Poly-Proline Helix Design: Round 2
Status: Closed
Created: 12/04/2019
Points: 100
Expired: 12/12/2019 - 23:00
Difficulty: Intermediate
Description: This is the second puzzle in our poly-proline helix design series! This is an 80 residue protein with a 12-residue long frozen poly-proline helix, and designable residues on either side. Just like in Round 1, it will be necessary to satisfy the exposed oxygens on the helix backbone to ensure that the protein stays folded! Globular structures with a hydrophobic core will have the best chance of folding in the real world.

Incorporating poly-proline helices into Foldit will help us design and make proteins with this new element! We are continuing to analyze your designs and improve the game to facilitate work with poly-proline helices.
Categories: Design, Overall

Top Groups

1Go Science11,008100
2Void Crushers10,88276
4Beta Folders10,84541
5Anthropic Dreams10,75929

Top Evolvers

Top Soloists

Need this puzzle? Log in to download.  


neilpg628's picture
User offline. Last seen 46 weeks 3 days ago. Offline
Joined: 08/01/2019
Groups: Foldit Staff

Residue Count (max +100)
Penalizes a residue count above 80 by 20 Foldit points per additional residue.

User login
Download links:
  Windows    OSX    Linux  
(10.12 or later)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media

Only search fold.it
Other Games: Mozak
Recommend Foldit
Top New Users

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons