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1764: Symmetric Trimer Design: H-Bond Networks
Status: Closed
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Soloists
1 | Enzyme 48 5 | Gargleblasters | 19,970 | 100 | 2 | LociOiling 8 3 | Beta Folders | 19,898 | 96 | 3 | ZeroLeak7 22 1 | Go Science | 19,872 | 92 | 4 | Bruno Kestemont 2 8 | Go Science | 19,688 | 88 | 5 | grogar7 64 4 | Anthropic Dreams | 19,656 | 84 | 6 | silent gene 7 11 | Go Science | 19,514 | 81 | 7 | spvincent 35 14 | Contenders | 19,484 | 77 | 8 | frood66 91 2622 | Marvin's bunch | 19,249 | 74 | 9 | retiredmichael 91 1639 | Beta Folders | 19,245 | 70 | 10 | hpaege 91 90 | | 19,208 | 67 | 11 | Galaxie 6 9 | Anthropic Dreams | 19,055 | 64 | 12 | johnmitch 91 12 | | 19,019 | 61 | 13 | robgee 12 15 | Anthropic Dreams | 18,946 | 58 | 14 | Timo van&n... 91 498 | Void Crushers | 18,923 | 55 | 15 | neon_fuzz 91 2622 | Go Science | 18,901 | 53 | 16 | Skippysk8s 19 25 | Gargleblasters | 18,880 | 50 | 17 | drumpeter18yrs9yrs 91 64 | | 18,756 | 48 | 18 | Blipperman 28 40 | Gargleblasters | 18,727 | 45 | 19 | Phyx 59 33 | Go Science | 18,695 | 43 | 20 | fiendish_ghoul 91 17 | | 18,552 | 41 | 21 | phi16 14 18 | Anthropic Dreams | 18,548 | 39 | 22 | Glen B 91 845 | | 18,307 | 37 | 23 | NinjaGreg 24 19 | Go Science | 18,285 | 35 | 24 | O Seki To 91 2622 | Hun-Magyar Csapat | 18,267 | 33 | 25 | ManVsYard 91 1639 | Gargleblasters | 17,920 | 30 | Need this puzzle? Log in to download.
Comments
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Core Existence: Monomer (max +1900)
Ensures that at least 19 residues are buried in the core of the monomer unit.
Core: Complex (max +0)
Awards no bonuses or penalties. Click Show to see which residues count as "Core" for the H-bond Network objective.
H-bond Network:
Rewards networks that comprise at least two H-bonds involving core residues.
Between 1 and 9 H-bonds should cross the interface between symmetric units.
Networks must be at least 75% satisfied (i.e. 75% of all bondable atoms in a network must make a H-bond).
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.