puzzle picture
1748: IL-7R Binder Redesign: Round 22
Status: Closed

Groups

RankGroupScorePoints
1Gargleblasters11,200100
2Go Science11,14565
3Anthropic Dreams11,10141
4Beta Folders10,99024
5L'Alliance Francophone10,84414
6Contenders10,8377
7Void Crushers10,8184
8Russian team10,7782
9Hun-Magyar Csapat10,7451
10Marvin's bunch10,6421
11Italiani Al Lavoro9,8551
12Trinity Biology9,6431
13Hold My Beer9,5161


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bkoep's picture
User offline. Last seen 18 hours 56 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Objectives

Residue IE Score (max +500)
Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence (max +1000)
Ensures that at least 25% of residues are buried in the protein core.

SS Design (max +200)
Penalizes all CYS residues. Penalizes GLY, ALA, SER, THR in helices. Penalizes GLY, ALA in sheets.

Residue Count (max +100)
Penalizes extra residues inserted beyond 110, at a cost of 20 points per residue. Players may use up to 115 residues in total.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons