puzzle picture
1730: IL-7R Binder Redesign: Round 13
Status: Closed

Groups

RankGroupScorePoints
1Go Science11,458100
2Contenders11,43571
3Gargleblasters11,40149
4Anthropic Dreams11,34733
5Marvin's bunch11,28022
6Beta Folders11,27914
7L'Alliance Francophone11,2498
8Void Crushers11,0305
9Hun-Magyar Csapat11,0053
10Russian team10,9952
11Hold My Beer10,9841
12BOINC@Poland10,5131
13Italiani Al Lavoro10,3671
14Kotocycle10,3471
15DSN @ Home8,8701
16FoldIt@Netherlands5,9341


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Comments

Joined: 06/24/2008
Groups: Void Crushers
Bad Residues

It would help if we knew How many bad residues are built into the puzzle so we didn't have waste time trying to find any bad residues that need to be corrected.

bkoep's picture
User offline. Last seen 10 hours 4 min ago. Offline
Joined: 11/15/2012
Groups: None
Objectives details

We didn't post the details for the Objectives in this puzzle, sorry for the oversight! See the comment below.

bkoep's picture
User offline. Last seen 10 hours 4 min ago. Offline
Joined: 11/15/2012
Groups: None
Objectives

Residue IE Score (max +500)
Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence (max +1000)
Ensures that at least 25% of residues are buried in the protein core.

SS Design (max +300)
Penalizes all CYS residues. Penalizes GLY, ALA, SER, THR in helices. Penalizes GLY, ALA in sheets.

Residue Count (max +100)
Penalizes extra residues inserted beyond 110, at a cost of 20 points per residue. Players may use up to 115 residues in total.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons