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1726: IL-7R Binder Redesign: Round 11
Status: Closed
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Evolvers
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| 1 | LociOiling 2 1 | Beta Folders | 11,984 | 100 | | 2 | dbuske 46 426 | Beta Folders | 11,947 | 94 | | 3 | Galaxie 1 2 | Anthropic Dreams | 11,868 | 88 | | 4 | mberna00 46 949 | Anthropic Dreams | 11,861 | 82 | | 5 | lamoille 46 1603 | Anthropic Dreams | 11,860 | 72 | | 6 | phi16 9 30 | Anthropic Dreams | 11,859 | 67 | | 7 | alcor29 5 9 | Anthropic Dreams | 11,858 | 62 | | 8 | robgee 7 6 | Anthropic Dreams | 11,858 | 58 | | 9 | Bruno Kestemont 3 3 | Go Science | 11,804 | 54 | | 10 | ManVsYard 46 526 | Gargleblasters | 11,704 | 50 | | 11 | Bletchley Park 8 7 | Contenders | 11,673 | 46 | | 12 | georg137 18 34 | Contenders | 11,651 | 43 | | 13 | Willyanto 46 1603 | Go Science | 11,613 | 40 | | 14 | silent gene 24 78 | Go Science | 11,613 | 37 | | 15 | fpc 12 40 | Marvin's bunch | 11,602 | 34 | | 16 | Museka 46 308 | L'Alliance Francophone | 11,572 | 31 | | 17 | Alistair69 46 112 | L'Alliance Francophone | 11,532 | 29 | | 18 | jausmh 17 29 | Marvin's bunch | 11,517 | 26 | | 19 | actiasluna 46 1603 | Gargleblasters | 11,480 | 24 | Need this puzzle? Log in to download.
Comments
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Residue IE Score (max +500)
Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence (max +1000)
Ensures that at least 25% of residues are buried in the protein core.
SS Design (max +200)
Penalizes all CYS residues. Penalizes GLY, ALA, SER, THR in helices. Penalizes GLY, ALA in sheets.
Residue Count (max +100)
Penalizes extra residues inserted beyond 110, at a cost of 20 points per residue. Players may use up to 115 residues in total.