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1722: Symmetric Trimer Design: 60 Residues
Status: Closed
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Evolvers
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| 1 | LociOiling 2 1 | Beta Folders | 17,108 | 100 | | 2 | Angus 46 1458 | Beta Folders | 17,100 | 95 | | 3 | silent gene 24 66 | Go Science | 17,056 | 89 | | 4 | Anfinsen_slept_here 21 53 | Go Science | 17,055 | 84 | | 5 | NinjaGreg 37 13 | Go Science | 17,039 | 79 | | 6 | Skippysk8s 34 28 | Gargleblasters | 17,020 | 74 | | 7 | actiasluna 46 1458 | Gargleblasters | 17,019 | 70 | | 8 | Bruno Kestemont 3 2 | Go Science | 17,016 | 66 | | 9 | Hollinas 46 1458 | Go Science | 17,013 | 62 | | 10 | Phyx 46 109 | Go Science | 17,002 | 58 | | 11 | Galaxie 1 3 | Anthropic Dreams | 16,939 | 54 | | 12 | Norrjane 46 377 | Gargleblasters | 16,938 | 51 | | 13 | lamoille 46 1458 | Anthropic Dreams | 16,899 | 44 | | 14 | robgee 7 6 | Anthropic Dreams | 16,896 | 41 | | 15 | phi16 9 29 | Anthropic Dreams | 16,775 | 38 | | 16 | alcor29 5 9 | Anthropic Dreams | 16,773 | 36 | | 17 | anthion 46 454 | Gargleblasters | 16,770 | 33 | | 18 | Primalsoul 46 1458 | Gargleblasters | 16,751 | 31 | | 19 | Willyanto 46 1458 | Go Science | 16,597 | 29 | | 20 | fpc 12 39 | Marvin's bunch | 16,582 | 27 | | 21 | jausmh 17 30 | Marvin's bunch | 16,446 | 25 | | 22 | TurtleByte 46 1458 | Go Science | 11,706 | 23 | Need this puzzle? Log in to download.
Comments
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Core Existence: Monomer (max +3000)
Ensures that at least 16 residues are buried in the core of the monomer unit.
Core Limit: Complex (max +500)
Checks that no more than 60 residues are buried in the symmetric complex, including the interface between monomer units.
SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.
Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.