puzzle picture
1684: Symmetric Dimer Design: 60 Residues
Status: Closed

Groups

RankGroupScorePoints
1Gargleblasters17,472100
2Go Science17,46068
3Anthropic Dreams17,18344
4Marvin's bunch17,16427
5Beta Folders17,16116
6Void Crushers16,7919
7Contenders16,7385
8Russian team16,3043
9L'Alliance Francophone16,2541
10Hun-Magyar Csapat16,0091
11I3L GANG13,9371
12Extraterrestrials 2.012,8371
13Mojo Risin'10,8391
14SETI.Germany7901


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Comments

bkoep's picture
User offline. Last seen 1 hour 41 min ago. Offline
Joined: 11/15/2012
Groups: None
Objectives

Core Existence: Monomer (max +1700)
Ensures that at least 17 residues are buried in the core of the monomer unit.

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

Secondary Structure (max +500)
No more than 50% of residues may form helices. Extra helices are penalized at 10 points per residue.

LociOiling's picture
User offline. Last seen 2 hours 52 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders
no core exists for the complex

The conditions don't mind if the two chains are far apart. Of course, your score may improve if they are....

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons