bkoep's picture
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Objectives

Core Existence: Monomer (max +2000)
Ensures that at least 20 residues are buried in the core of the monomer unit.

Core Existence: Complex (max +2300)
Ensures that at least 46 residues are buried in the core of the entire complex (including the interface between monomer units).

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

Secondary Structure (max +500)
No more than 50% of residues may form helices. Extra helices are penalized at 10 points per residue.

grogar7's picture
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Ideal Loops filter is not present

Do the devs want to repost or leave it as is?

bkoep's picture
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Sorry for the oversight!

Thanks for pointing this out! That was an error in the Objectives description. The puzzle will stay!

jeff101's picture
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Groups: Go Science
Puzzle 1665 images

Puzzle 1665 images have been posted at:
https://foldit.fandom.com/wiki/Puzzle_1665

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons