puzzle picture
1623: Symmetric Dimer Design
Status: Closed

Groups

RankGroupScorePoints
1Beta Folders20,663100
2Gargleblasters20,61173
3Anthropic Dreams20,60652
4Contenders20,58536
5Go Science20,51324
6Void Crushers20,23216
7Russian team20,17610
8L'Alliance Francophone20,1626
9Marvin's bunch19,8914
10Team South Africa17,6992
11Hun-Magyar Csapat17,2251
12FoldIt@Poland16,1471
13Hold My Beer15,5211
14Italiani Al Lavoro15,4651
15DW 202014,8551
16Otterbein Cell Biology 2019 Foldit13,3881
17Rechenkraft.net10,2801


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bkoep's picture
User offline. Last seen 4 hours 54 min ago. Offline
Joined: 11/15/2012
Groups: None
Objectives

Core Existence: Monomer (max +2000)
Ensures that at least 20 residues are buried in the core of the monomer unit.

Core Existence: Complex (max +2400)
Ensures that at least 48 residues are buried in the core of the entire complex (including the interface between monomer units).

SS Design (max +500)
Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.

Ideal Loops (max +500)
Penalizes any loop region that does not match one of the Building Blocks in the Blueprint tool. Use "Auto Structures" to see which regions of your protein count as loops.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons