cis peptide bonds
|Opened on:||Monday, December 10, 2018 - 23:58|
|Last modified:||Thursday, June 2, 2022 - 00:17|
Suppose you are trying to solve a protein containing a cis peptide bond.
Fig.3 of https://www.open.edu/openlearn/science-maths-technology/science/biology/proteins/content-section-1.2 (https://www.open.edu/openlearn/ocw/mod/oucontent/view.php?id=2527&extra=thumbnail_idp960592),
attached below, shows how cis peptide bonds differ from trans ones.
https://fold.it/portal/node/995580#comment-24061 says that cis peptide
bonds are quite rare compared to trans ones (the trans:cis ratio is
usually about 1000:1, but near prolines it can be 3:1). Which Foldit
tools are most likely to add a cis peptide bond to your solution?
Which Foldit tools are most likely to remove any cis peptide bonds
from your solution?