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1608: Symmetric Dimer Design: Hydrogen Bond Networks
Status: Closed


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bkoep's picture
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Core Existence: Monomer (max +1900)
Ensures that at least 19 residues are buried in the core of the monomer unit. The threshold of "buriedness" between core and surface residues is more stringent than usual, so residues may have to be "extra buried" to be counted toward the core.

Core Existence: Complex (max +2100)
Ensures that at least 42 residues are buried in the core of the entire complex (including the interface between monomer units).

HBond Network
Rewards networks that comprise at least three hydrogen bonds involving core residues. Networks must be at least 70% satisfied (i.e. 70% of all oxygens and polar hydrogens in a network must make a hydrogen bond).

SS Design (max +500)
Prohibits all CYS residues. Prohibits GLY, ALA residues in sheets and helices.

toshiue's picture
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two 1607s

this one is really 1608?

bkoep's picture
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Sorry for the oversight, this has been corrected!

dbuske's picture
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2nd chain

I cannot find the 2nd chain, then I lost the 1st chain.
Q does not work to find the 1st chain.

Joined: 01/24/2016
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That has happened to me in

That has happened to me in the past. If the 2 chains get too far apart, then Q will not work. Q will center the midpoint of the 2 chains. Also, if you rotate them like that, the "dimming" lighting effect will make the 1st chain disappear.

Either move the chain so that the ends furthest apart are nearer;

from: 111111111111111 2222222222222222

to: 111111111111111

at the start of the game, or use a band to anchor one end of chain 1, before running any recipes.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons