Let certain Design Puzzles input one or more pdb or ir_solution files to make starting structures
|Case number:||845813-2006295 |
|Topic:||Game: Tools |
|Opened by:||jeff101 |
|Opened on:||Friday, December 7, 2018 - 14:21 |
|Last modified:||Monday, March 11, 2019 - 00:28 |
I know many have asked for the ability to import pdb files
into Foldit before, but maybe this ability would help more
than it hurts for certain Design Puzzles. I think it would
be interesting to see what we could design by taking parts
of known proteins and loading them into Foldit via one or
more pdb files. Once the starting structure was loaded in,
we could mutate its residues to improve its design.
Similarly, it would be interesting if we could import our
solutions from previous puzzles into a Design Puzzle via
our old ir_solution files. This would let us improve on
old designs, perhaps making our top scores on each Design
Puzzle a little higher each time. Loading at least one
ir_solution file from an old evo could make the new design
count as an evo from the start.
Perhaps we could combine several pdb and ir_solution files
to make our starting structure. If multiple files were used,
Foldit could have the first file give residues 1 to L, the
2nd file give residues L+1 to M, the 3rd file give residues
M+1 to N, etc. This would work as long as the final total #
of residues was in the desired range for the Design Puzzle.
There could be long blue cut bands between residues L and
L+1, M and M+1, N and N+1, etc. We would have to find ways
to shorten these blue cut bands enough that they became
yellow, at which point we could heal/remove them.