puzzle picture
Partition Puzzle (B): Galaxie
Status: Closed

Summary

Name: Partition Puzzle (B): Galaxie
Status: Closed
Created: 09/18/2018
Points: 0
Expired: 10/16/2018 - 23:00
Difficulty: Expert
Description: This is a partition puzzle for Phase Two of the Partition Tournament! The starting structure is a design by Galaxie from Phase One of the tournament, and is now vulnerable to challenges. Players can challenge the design by playing this puzzle and refolding the starting structure into other high-scoring structures. The starting structure is marked with secondary structure predictions from PSIPRED, and may give clues about how this protein could be refolded. This design will ultimately be evaluated by how well it withstands challenges, as measured by the partition function. See the blog for more details about the Protein Design Partition Tournament.
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Comments

Joined: 09/24/2012
Groups: Go Science
Target

12230 pts (score of the original pose).
11930 for a first challenging partition

actiasluna's picture
User offline. Last seen 1 hour 48 min ago. Offline
Joined: 03/05/2015
Groups: Gargleblasters
Hi Bruno, would you mind

Hi Bruno, would you mind explaining your "Target" comments a bit more for the non-experts (like me)?
Thanks!

Joined: 09/24/2012
Groups: Go Science
Hi Actiasluna

The first target is the score of the original pose (this is the score that you see when you reset the puzzle). If you get more than this, this is bad news for the first round.

The smaller target is the minimum needed in order to figure in the partition function. Smaller scores are not really challenging the original design.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons