puzzle picture
Partition Puzzle (B): manu8170
Status: Closed


Name: Partition Puzzle (B): manu8170
Status: Closed
Created: 09/18/2018
Points: 0
Expired: 10/15/2018 - 23:00
Difficulty: Expert
Description: Note: This puzzle was closed early, because challengers found decoy states with lower energy than the initial design. Try one of the other partition puzzles!

This is a partition puzzle for Phase Two of the Partition Tournament! The starting structure is a design by manu8170 from Phase One of the tournament, and is now vulnerable to challenges. Players can challenge the design by playing this puzzle and refolding the starting structure into other high-scoring structures. The starting structure is marked with secondary structure predictions from PSIPRED, and may give clues about how this protein could be refolded. This design will ultimately be evaluated by how well it withstands challenges, as measured by the partition function. See the blog for more details about the Protein Design Partition Tournament.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons