I was able to load one puzzle 1519 solution.
After saving the solution for puzzle 1573, the client hung during the upload.
Another client could see the share for 1573, but hung trying to download it.
After restarting the second client, the downloaded solution appeared twice, but the client hung trying to upload it.
Back on the first client, trying to open a different, locally-saved solution for 1519 resulted in a hang.
Working on a feedback, just an early warning....
I'm hanging on loading 1573 tracks.
I've hung when doing some operation. When I get back into foldit and try to go to that track, it hangs.
Similar here. It crashed on me and subsequent attempts to play the puzzle also result in a crash on opening.
Main/Ubuntu 18.04
hangs terribly on download, managed to mae one create a valid save point, cannot download solution to other clients, all fresh clients, just opened
Interesting, i got my score on the table then it crashed. Now the interesting thing is when an operation is approaching my registered score it crashes. I have tried umpteen times and whenever i get near that scoreboard score it crashes, whether i be shaking, wiggling or wiggling sidechains.
Oh Yeah, i couldnt get any recipes to run at all, instant hang.
Seconding this comment. I've probably experienced 20 hangs in the midst of shakes and wiggles, all of which took place within 10 points of my current best score. Unplayable for me in its current state
Win10/64; Main, Original UI. Tried to load atom and hung. Second attempt tried wiggle and it hung. Not playable as is.
Yep, slowness and hangs for me also
Are you going to fix this puzzle???
hangs on every share, both machines, any client, any share. haven't been able to dl one share yet.
This link is scholarly; Current articles on advances on drug design ligand inhibitors.
I would practice building some of these to get an idea of how to make your own. That's what I'm going to do anyway.
https://pubs.acs.org/toc/jmcmar/0/0
Besides crashing ever 2 minutes, this puzzle is running fine.
here
https://fold.it/portal/node/2005702
Hang on all track changes and/or loading shared solutions.
(Windows + Linux)
No problem with old Mac OS.
Multiple hangs and crashes.............fix coming soon?
(Windows)
still can't load any shares, no evo available. this just isn't a viable puzzle. may we withdraw it until it's fixed please?
still refuses to load any group shares, unable to start evo on either Win7 or Win10 machine. puzzle is 2/3s over and haven't been able to start an evo yet. please withdraw this puzzle and fix it.
Molecular Weight (max 2000 pts): Penalizes larger (over 630 Da) small molecules.
Number of Rotatable Bonds (max 1000 pts): Penalizes very flexible small molecules. (Click "Show" to highlight rotatable bonds.) Bonds in rings don't count as "rotatable".
Ligand Substructures (max 1000 pts): Penalizes substructures which either occur rarely in drug like molecules, or were over-represented in previous rounds:
Synthetic Accessibility (max 1000 pts): Penalizes compounds which are harder to make. (Click "Show" to show troublesome areas of the molecule.)
Ligand Hydrogen Bond Acceptors (max 1000 pts): Penalizes compounds with too many (14 or more) hydrogen bond acceptors.
Ligand Hydrogen Bond Donors (max 1000 pts): Penalizes compounds with too many (7 or more) hydrogen bond donors.
Ligand cLogP (max 1000 pts): Penalizes compounds which are too hydrophobic.