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1566: Small Monomer Design
Status: Closed

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bkoep's picture
User offline. Last seen 14 hours 37 min ago. Offline
Joined: 11/15/2012
Groups: None
Objectives

Interaction Energy: Monitors that all PHE, TYR, and TRP residues are scoring well.

SS Design: Prohibits all CYS residues. Prohibits GLY, ALA residues in sheets. Prohibits GLY, ALA, SER, THR in helices.

Residue Count: Normalizes for extra residues inserted beyond the starting 65, at a cost of 32 points per residue. Players may use up to 75 residues in total.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons