|
1552: Find the Hydrogen Bond Networks!
Status: Closed
|
Summary
| Name: | 1552: Find the Hydrogen Bond Networks! |
|---|---|
| Status: | Closed |
| Created: | 07/21/2018 |
| Points: | 100 |
| Expired: | 07/28/2018 - 23:00 |
| Difficulty: | Intermediate |
| Description: | This puzzle is a little different from other prediction puzzles in Foldit. This protein is a dimer (i.e. two chains fold up and bind each other) that was designed in the Baker Lab. The design has two identical H-bond networks that span the interface between the two chains. In order to solve this puzzle, Foldit players will have to fold each of the two chains, bring them together, and arrange the interface to form the two H-bond networks. The secondary structure of the designed protein is marked on the starting structure. See if you can fold this protein and find the H-bond networks! |
| Categories: | Overall, Prediction |
Top Groups
Top Evolvers
Top Soloists
Need this puzzle? Log in to download.
Core Existence: Complex: Ensures that at least 48 residues are buried in the core of the entire complex (including the interface between monomer units).
HBond Network: Rewards networks that comprise at least three hydrogen bonds involving core residues. Networks must be at least 75% satisfied (i.e. 75% of all polar atoms in a network must make a hydrogen bond).