|
1509: Small Monomer Design
Status: Closed
|
Summary
| Name: | 1509: Small Monomer Design |
|---|---|
| Status: | Closed |
| Created: | 04/17/2018 |
| Points: | 100 |
| Expired: | 04/24/2018 - 23:00 |
| Difficulty: | Intermediate |
| Description: | This puzzle challenges players to design a single-chain protein with 65-75 residues. The starting structure has 65 residues, but more can be added at a cost of 32 points per residue. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions! |
| Categories: | Design, Overall |
Top Groups
Top Evolvers
Top Soloists
Need this puzzle? Log in to download.
Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
SS Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets. Penalizes GLY, ALA, SER, THR in helices.
Residue Count: Penalizes extra residues inserted beyond the starting 65, at a cost of 32 points per residue. Players may use up to 75 residues in total.