bkoep's picture
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Joined: 11/15/2012
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Filters

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.

Residue Count: Penalizes extra residues inserted beyond the starting 85 70. Players may use up to 105 90 residues in total.

NinjaGreg's picture
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Joined: 05/21/2010
Groups: Go Science
Something wrong with the filters?

It shows I have 75 residues, and it says it's 5 over the limit of 70. I haven't added any so what you've said above about starting with 85 is incorrect, also.

LociOiling's picture
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Joined: 12/27/2012
Groups: Beta Folders
Looks like it started with 75...

I'm seeing 75 segments at the start, and was able to add up to 90. Looks like the comment in the filters was copied from another puzzle.

bkoep's picture
User offline. Last seen 7 hours 50 min ago. Offline
Joined: 11/15/2012
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Sorry!

You're right, there are some problems with this puzzle's setup. The puzzle should probably have started with 70 residues.

Since the puzzle is still technically functional, we won't bother pulling and reposting it; I've edited the comment and puzzle description above.

To clarify: Every additional residue beyond 70 will incur a 23 point penalty, and a maximum of 90 residues are allowed.

Joined: 03/05/2015
Groups: Gargleblasters
Please check also this feedback... unplayable on my machine
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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