puzzle picture
Beginner Puzzle (<150): Symmetry Design
Status: Closed

Summary

Name: Beginner Puzzle (<150): Symmetry Design
Status: Closed
Created: 01/27/2014
Points: 100
Expired: 03/15/2018 - 23:00
Difficulty: Beginner
Description: This is a small symmetric trimer design puzzle. A symmetric protein relies not only on how well folded each part is, but also on how well they interface together. Your changes will be reflected in the symmetric unit. Make sure you have completed Intro Puzzle 5-2, and 7-1 through 7-4. For players with fewer than 150 global points.

START HERE:

If you are new to Foldit, here are detailed instructions to get you started:
http://fold.it/portal/node/988864
_____________________________

If you want to fold proteins, know that there are many ways to play and this variety is the main value of Foldit :
- try all puzzles not only "Beginners" ones,
- fold first the ones you like the most,
- try it by yourself to understand what works and what doesn't,
- ask for tips in global chat when you think you don't understand something.

Make sure you have followed these tutorials:
- Lonely Sheets,
- Lock and Lower,
- Rebuild,
- Structure and Rebuild,
- Movin' Along,
- Control over Clashing,
- Intro to Design,
- Swappin' Sidechains,
- Mass Mutate,
- Insertion and Deletion

before starting this puzzle.

Categories: Beginner

Top Groups

Top Soloists

RankPlayerGroupScorePoints
1pi r ... 80 111  10,969100
2Madde 40 16 Void Crushers10,90293
3FlippySpatula 80 83  10,71786
4Jayadev 80 67  10,63879
5Mr. Nice&n... 80 219  10,42973


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Comments

SaraL's picture
User offline. Last seen 14 hours 2 min ago. Offline
Joined: 09/20/2011
Groups: Gargleblasters
Instant Crash

Testing out the symmetry puzzle - I did something simple. I made one end a helix and the other end a sheet. Did Ideal SS on the helix, froze it, then went to pull the sheet into position - the client crashed instantly.

LociOiling's picture
User offline. Last seen 2 hours 4 min ago. Offline
Joined: 12/27/2012
Groups: Beta Folders
May be crashy...

Symmetry puzzles haven't been working right in quite a while.

I tried this one, and got a crash on Windows when I followed the general steps SaraL listed. Pulling on the sheet seemed to cause the crash.

I got a little further using cutpoints, but hit a crash again a few minutes later while running a recipe.

Obviously some people are either lucky or very persistent and are able to make progress despite the crashes.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Microsoft, Adobe, RosettaCommons