puzzle picture
1460: Large Monomer Design
Status: Closed

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18DSN @ Home01


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bkoep's picture
User offline. Last seen 6 hours 29 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 35% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.

Residue Count: Penalizes extra residues inserted beyond the starting 85. Players may use up to 105 residues in total.

Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."

Joined: 03/05/2015
Groups: Gargleblasters
Puzzle end extended?

Was this puzzle's expiration date extended due to the chat issues? This morning it is giving me 7 days 10 hours when I swear yesterday it said 4.

bkoep's picture
User offline. Last seen 6 hours 29 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
No

Hmm, that's strange. We haven't changed the expiration date since the puzzle was posted.

Joined: 09/24/2012
Groups: Go Science
This said

I appreciate to have time for design puzzles

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons