puzzle picture
1460: Large Monomer Design
Status: Closed


2Beta Folders10,80774
3Go Science10,74654
4Anthropic Dreams10,72238
6Void Crushers10,55118
7L'Alliance Francophone10,23312
8Marvin's bunch10,0858
9GENE 4339,9175
10Another Hour Another Point9,5473
12Team South Africa8,6261
14E?????! Heureka!8,0191
15BCC 7,9661
16Mojo Risin'3,9371
17Clear the Way01
18DSN @ Home01

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bkoep's picture
User offline. Last seen 6 hours 29 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 35% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.

Residue Count: Penalizes extra residues inserted beyond the starting 85. Players may use up to 105 residues in total.

Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."

Joined: 03/05/2015
Groups: Gargleblasters
Puzzle end extended?

Was this puzzle's expiration date extended due to the chat issues? This morning it is giving me 7 days 10 hours when I swear yesterday it said 4.

bkoep's picture
User offline. Last seen 6 hours 29 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff

Hmm, that's strange. We haven't changed the expiration date since the puzzle was posted.

Joined: 09/24/2012
Groups: Go Science
This said

I appreciate to have time for design puzzles

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons