Sat, 09/23/2017 - 18:43
#2
Per-residue penalty
You might consider reducing the per-residue penalty a little bit since the core bonus is less. 23 has always been quite steep (that appears to be the regression coefficient only for the top 10 solutions on fixed-length puzzles, so that any solution worse than top 10 quality loses more than it can regain when adding residues). Now with a smaller overall filter bonus, the average points per residue are also reduced.
Sat, 09/30/2017 - 05:38
#3
Как интересно можно провести время?
Приветики мальчики и девочки. А как интересно Вы
проводите своё свободное время?
Sat, 09/30/2017 - 05:38
#4
Как интересно можно провести время?
Приветики мальчики и девочки. А как интересно Вы
проводите своё свободное время?
Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.
Residue Count: Penalizes extra residues inserted beyond the starting 75. Players may use up to 90 residues in total.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."