puzzle picture
1429: Revisiting Puzzle 140: Rosetta Decoy 4
Status: Closed

Summary

Name: 1429: Revisiting Puzzle 140: Rosetta Decoy 4
Status: Closed
Created: 09/12/2017
Points: 100
Expired: 09/20/2017 - 18:00
Difficulty: Intermediate
Description: This is a throwback puzzle to the early days of Foldit. This protein helps to regulate oxidation in the cell; the starting structure is a model produced by Rosetta. This protein contains four cysteine residues, but in this state only two of them are expected to oxidize to form a single disulfide bond. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been.

Sequence:
MPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYL
Categories: Overall, Prediction

Top Groups

RankGroupScorePoints
1Beta Folders9,991100
2Gargleblasters9,97173
3Anthropic Dreams9,94152
4Void Crushers9,93736
5Go Science9,92624

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons