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1407: Medium Monomer Design Puzzle: Larger Core
Status: Closed

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RankGroupScorePoints
1Beta Folders10,495100
2Anthropic Dreams10,48070
3Go Science10,40547
4Gargleblasters10,37230
5Marvin's bunch10,28419
6Contenders10,22611
7Void Crushers10,1417
8L'Alliance Francophone9,0654
9:)7,8192
10MU CLA BMB 465.3W17,6791
11E?????! Heureka!7,5881
12Russian team6,8821
13Piratenpartei Deutschland3,7871
14SETI.Germany2,9971
15Natural Abilities01


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bkoep's picture
User offline. Last seen 17 hours 17 min ago. Offline
Joined: 11/15/2012
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 35% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.

Residue Count: Penalizes extra residues inserted beyond the starting 75. Players may use up to 90 residues in total.

Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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