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1401: Small Monomer Design: Larger Core
Status: Closed


1Go Science10,208100
2Beta Folders10,20571
3Anthropic Dreams10,15549
6Marvin's bunch9,99814
7Void Crushers9,8698
8L'Alliance Francophone9,4795
9Hun-Magyar Csapat8,9973
10Italiani Al Lavoro8,9342
12Russian team8,4501
14MU CLA BMB 465.3W14,3411
16Natural Abilities01

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bkoep's picture
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 35% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.

Residue Count: Penalizes extra residues inserted beyond the starting 65. Players may use up to 75 residues in total.

Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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