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1358: 70 Residue Monomer Design: Helix Restrictions
Status: Closed
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Soloists
1 | LociOiling 2 1 | Beta Folders | 10,381 | 100 | 2 | gitwut 46 1458 | Contenders | 10,357 | 97 | 3 | MurloW 46 1458 | Anthropic Dreams | 10,318 | 94 | 4 | ZeroLeak7 46 97 | Go Science | 10,304 | 90 | 5 | markm457 46 1458 | Anthropic Dreams | 10,301 | 87 | 6 | tokens 46 1458 | Anthropic Dreams | 10,273 | 84 | 7 | retiredmichael 46 1458 | Beta Folders | 10,268 | 81 | 8 | Bruno Kestemont 3 2 | Go Science | 10,265 | 78 | 9 | actiasluna 46 1458 | Gargleblasters | 10,264 | 75 | 10 | Blipperman 26 33 | Gargleblasters | 10,255 | 72 | 11 | Susume 46 201 | Anthropic Dreams | 10,248 | 70 | 12 | Bletchley Park 8 8 | Contenders | 10,237 | 67 | 13 | Galaxie 1 3 | Anthropic Dreams | 10,236 | 64 | 14 | dcrwheeler 46 4 | | 10,207 | 62 | 15 | kabubi 46 1458 | Void Crushers | 10,178 | 60 | 16 | fiendish_ghoul 46 34 | | 10,158 | 55 | 17 | Timo van&n... 46 49 | Void Crushers | 10,129 | 53 | 18 | caglar 46 1458 | Go Science | 10,126 | 51 | 19 | hpaege 46 1458 | | 10,122 | 49 | 20 | mimi 46 1458 | Contenders | 10,115 | 47 | 21 | Vinara 46 57 | | 10,086 | 45 | 22 | stomjoh 46 92 | | 10,081 | 43 | 23 | spvincent 29 12 | Contenders | 10,059 | 41 | 24 | Museka 46 1458 | L'Alliance Francophone | 10,057 | 40 | 25 | isaksson 46 1458 | Go Science | 10,011 | 38 | Need this puzzle? Log in to download.
Comments
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.
Residue Count: Penalizes extra residues inserted beyond the 70 residue limit. Players may insert up to 10 extra residues.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."