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1358: 70 Residue Monomer Design: Helix Restrictions
Status: Closed
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Groups
1 | Beta Folders | 10,381 | 100 |
2 | Contenders | 10,370 | 77 |
3 | Anthropic Dreams | 10,336 | 58 |
4 | Go Science | 10,304 | 43 |
5 | Gargleblasters | 10,264 | 31 |
6 | Void Crushers | 10,178 | 22 |
7 | L'Alliance Francophone | 10,057 | 15 |
8 | Italiani Al Lavoro | 9,435 | 11 |
9 | Kotocycle | 9,204 | 7 |
10 | D001x Med Chem MOOC | 9,044 | 5 |
11 | Richard Dawkins Foundation | 8,679 | 3 |
12 | Russian team | 8,565 | 2 |
13 | Team South Africa | 8,560 | 1 |
14 | GUGITBIOTECH | 8,389 | 1 |
15 | xkcd | 8,249 | 1 |
16 | Hentainase | 7,915 | 1 |
17 | SFASU_BIO448/548 | 7,093 | 1 |
18 | E?????! Heureka! | 6,221 | 1 |
19 | Natural Abilities | 0 | 1 |
20 | DSN @ Home | 0 | 1 |
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Comments
Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.
Residue Count: Penalizes extra residues inserted beyond the 70 residue limit. Players may insert up to 10 extra residues.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."