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1352: 90 Residue Monomer Design: Helix Restrictions
Status: Closed
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Evolvers
1 | reefyrob 45 1456 | Beta Folders | 10,846 | 100 | 2 | LociOiling 3 1 | Beta Folders | 10,846 | 97 | 3 | smilingone 45 1456 | Beta Folders | 10,845 | 94 | 4 | Galaxie 1 3 | Anthropic Dreams | 10,831 | 92 | 5 | lamoille 45 1456 | Anthropic Dreams | 10,807 | 86 | 6 | phi16 9 28 | Anthropic Dreams | 10,804 | 83 | 7 | alwen 45 1456 | Anthropic Dreams | 10,784 | 81 | 8 | Blipperman 26 33 | Gargleblasters | 10,779 | 78 | 9 | Skippysk8s 34 27 | Gargleblasters | 10,773 | 76 | 10 | ManVsYard 45 452 | Gargleblasters | 10,773 | 73 | 11 | Keresto 41 430 | Gargleblasters | 10,773 | 71 | 12 | Bruno Kestemont 2 2 | Go Science | 10,766 | 68 | 13 | andrewxc 45 474 | Gargleblasters | 10,763 | 66 | 14 | alcor29 5 9 | Anthropic Dreams | 10,750 | 64 | 15 | retiredmichael 45 1456 | Beta Folders | 10,723 | 62 | 16 | toshiue 45 860 | Go Science | 10,723 | 60 | 17 | Hollinas 45 1456 | Go Science | 10,693 | 58 | 18 | uihcv 45 1456 | Go Science | 10,683 | 56 | 19 | Paulo Roque 45 1456 | Go Science | 10,671 | 54 | 20 | Bletchley Park 8 7 | Contenders | 10,591 | 52 | 21 | mimi 45 1456 | Contenders | 10,559 | 50 | 22 | randomlil 45 1456 | Beta Folders | 10,556 | 48 | 23 | georg137 18 35 | Contenders | 10,533 | 47 | 24 | dbuske 45 1456 | Beta Folders | 10,498 | 45 | 25 | NinjaGreg 37 14 | Go Science | 10,215 | 44 | Need this puzzle? Log in to download.
Comments
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.
Residue Count: Penalizes extra residues inserted beyond the 90 residue limit. Players may insert up to 10 extra residues.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."