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1349: 75 Residue Monomer Design: Helix Restrictions
Status: Closed
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Evolvers
1 | Fat Tony 45 1456 | Gargleblasters | 10,448 | 100 | 2 | Skippysk8s 34 27 | Gargleblasters | 10,448 | 97 | 3 | ManVsYard 45 452 | Gargleblasters | 10,448 | 94 | 4 | smilingone 45 1456 | Beta Folders | 10,445 | 91 | 5 | LociOiling 3 1 | Beta Folders | 10,445 | 88 | 6 | retiredmichael 45 1456 | Beta Folders | 10,443 | 85 | 7 | Blipperman 26 33 | Gargleblasters | 10,438 | 82 | 8 | smholst 45 1456 | Gargleblasters | 10,418 | 79 | 9 | reefyrob 45 1456 | Beta Folders | 10,399 | 76 | 10 | mimi 45 1456 | Contenders | 10,342 | 74 | 11 | Galaxie 1 3 | Anthropic Dreams | 10,341 | 71 | 12 | lamoille 45 1456 | Anthropic Dreams | 10,338 | 68 | 13 | phi16 9 28 | Anthropic Dreams | 10,337 | 66 | 14 | alwen 45 1456 | Anthropic Dreams | 10,335 | 64 | 15 | gitwut 45 1456 | Contenders | 10,334 | 61 | 16 | Bruno Kestemont 2 2 | Go Science | 10,331 | 59 | 17 | actiasluna 45 1456 | Gargleblasters | 10,296 | 57 | 18 | alcor29 5 9 | Anthropic Dreams | 10,277 | 55 | 19 | ViJay7019 45 1456 | Go Science | 10,203 | 53 | 20 | JayD7217 45 1456 | Go Science | 10,160 | 51 | 21 | dbuske 45 1456 | Beta Folders | 10,057 | 49 | 22 | Anfinsen_slept_here 20 53 | Go Science | 10,035 | 47 | 23 | Formula350 45 1456 | Gargleblasters | 8,900 | 45 | Need this puzzle? Log in to download.
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.
Residue Count: Penalizes extra residues inserted beyond the 75 residue limit. Players may insert up to 10 extra residues.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."