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1346: 80 Residue Monomer Design: Helix Restrictions
Status: Closed
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Soloists
1 | LociOiling 2 1 | Beta Folders | 10,558 | 100 | 2 | markm457 46 1458 | Anthropic Dreams | 10,555 | 98 | 3 | Bruno Kestemont 3 2 | Go Science | 10,554 | 95 | 4 | dcrwheeler 46 4 | | 10,547 | 92 | 5 | retiredmichael 46 1458 | Beta Folders | 10,544 | 89 | 6 | MurloW 46 1458 | Anthropic Dreams | 10,482 | 87 | 7 | Scopper 46 1458 | Go Science | 10,479 | 84 | 8 | Susume 46 201 | Anthropic Dreams | 10,461 | 82 | 9 | actiasluna 46 1458 | Gargleblasters | 10,457 | 79 | 10 | Timo van&n... 46 49 | Void Crushers | 10,443 | 77 | 11 | hpaege 46 1458 | | 10,440 | 74 | 12 | bertro 46 1458 | Beta Folders | 10,436 | 72 | 13 | isaksson 46 1458 | Go Science | 10,415 | 70 | 14 | gitwut 46 1458 | Contenders | 10,414 | 68 | 15 | tokens 46 1458 | Anthropic Dreams | 10,410 | 66 | 16 | Galaxie 1 3 | Anthropic Dreams | 10,409 | 64 | 17 | ZeroLeak7 46 97 | Go Science | 10,408 | 62 | 18 | kabubi 46 1458 | Void Crushers | 10,393 | 60 | 19 | spvincent 29 12 | Contenders | 10,384 | 58 | 20 | Museka 46 1458 | L'Alliance Francophone | 10,383 | 56 | 21 | fiendish_ghoul 46 34 | | 10,380 | 54 | 22 | shettler 46 550 | | 10,376 | 52 | 23 | Bletchley Park 8 8 | Contenders | 10,374 | 51 | 24 | reefyrob 46 1458 | Beta Folders | 10,360 | 47 | 25 | stomjoh 46 92 | | 10,328 | 46 | Need this puzzle? Log in to download.
Comments
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA residues in sheets; penalizes GLY, ALA, SER, THR in helices.
Residue Count: Penalizes extra residues inserted beyond the 80 residue limit. Players may insert up to 10 extra residues.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."