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1321: 90 Residue Monomer Design: Blueprint
Status: Closed
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Evolvers
1 | Galaxie 1 2 | Anthropic Dreams | 10,829 | 100 | 2 | tokens 46 1295 | Anthropic Dreams | 10,823 | 97 | 3 | smilingone 46 1295 | Beta Folders | 10,811 | 90 | 4 | reefyrob 46 1295 | Beta Folders | 10,810 | 86 | 5 | LociOiling 2 1 | Beta Folders | 10,809 | 83 | 6 | bertro 46 1295 | Beta Folders | 10,807 | 80 | 7 | phi16 11 32 | Anthropic Dreams | 10,805 | 77 | 8 | Blipperman 34 42 | Gargleblasters | 10,805 | 74 | 9 | Keresto 41 493 | Gargleblasters | 10,801 | 71 | 10 | ManVsYard 46 1003 | Gargleblasters | 10,800 | 68 | 11 | Superphosphate 46 1295 | Gargleblasters | 10,786 | 66 | 12 | SaraL 46 1295 | Gargleblasters | 10,785 | 63 | 13 | Skippysk8s 33 40 | Gargleblasters | 10,778 | 61 | 14 | lamoille 46 1295 | Anthropic Dreams | 10,767 | 58 | 15 | alwen 46 1295 | Anthropic Dreams | 10,744 | 56 | 16 | jamiexq 38 68 | Anthropic Dreams | 10,742 | 53 | 17 | alcor29 5 7 | Anthropic Dreams | 10,726 | 51 | 18 | hansvandenhof 46 477 | Anthropic Dreams | 10,718 | 49 | 19 | Bletchley Park 9 8 | Contenders | 10,703 | 47 | 20 | TomTaylor 46 1295 | Contenders | 10,686 | 45 | 21 | pauldunn 46 1295 | Go Science | 10,680 | 41 | 22 | Anfinsen_slept_here 15 38 | Go Science | 10,674 | 40 | 23 | Bruno Kestemont 3 3 | Go Science | 10,674 | 38 | 24 | JayD7217 46 1295 | Go Science | 10,672 | 36 | 25 | gitwut 46 1295 | Contenders | 10,667 | 35 | Need this puzzle? Log in to download.
Comments
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.
Residue Count: Penalizes extra residues inserted beyond the 90 residue limit. Players may insert up to 10 extra residues.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."