puzzle picture
1278: Revisiting Puzzle 69: Scorpion Toxin
Status: Closed

Summary

Name: 1278: Revisiting Puzzle 69: Scorpion Toxin
Status: Closed
Created: 08/31/2016
Points: 100
Expired: 09/07/2016 - 18:00
Difficulty: Intermediate
Description: This is a throwback puzzle to the early days of Foldit. This is another potent neurotoxin produced by scorpions, similar to that found in Puzzle 55. This protein contains eight cysteine residues that oxidize to form four disulfide bonds. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been.

Sequence:
MKKNGYPLDRNGKTTECSGVNAIAPHYCNSECTKVYYAESGYCCWGACYCFGLEDDKPIGPMKDITKKYCDVQI
Categories: Overall, Prediction

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Comments

bertro's picture
User offline. Last seen 22 min 11 sec ago. Offline
Joined: 05/02/2011
Groups: Beta Folders
Crash with latest devprev

on win10. No debug.txt or log.txt crash info in the files. Was running a script.

bertro's picture
User offline. Last seen 22 min 11 sec ago. Offline
Joined: 05/02/2011
Groups: Beta Folders
again

ending of log.txt:

***** STARTING THREAD ActionGlobalMinimize
***** ENDING THREAD ActionGlobalMinimize
***** STARTING THREAD ActionIdealize
***** ENDING THREAD ActionIdealize
***** STARTING THREAD ActionGlobalMinimize
Sending SOPs:

IRC::run error, code = 5, desc = Remote connection closed
Exiting IRC::run
***** ENDING THREAD ActionGlobalMinimize
***** STARTING THREAD ActionIdealize
***** ENDING THREAD ActionIdealize
***** STARTING THREAD ActionGlobalMinimize
Sending SOPs:

Entering IRC::run
***** ENDING THREAD ActionGlobalMinimize
***** STARTING THREAD ActionIdealize
IRC::run error, code = 5, desc = Remote connection closed
Exiting IRC::run

bertro's picture
User offline. Last seen 22 min 11 sec ago. Offline
Joined: 05/02/2011
Groups: Beta Folders
third time

same thing, no crash info at all.

End of log.txt file:

***** STARTING THREAD ActionIdealize
***** ENDING THREAD ActionIdealize
***** STARTING THREAD ActionGlobalMinimize
IRC::run error, code = 5, desc = Remote connection closed
Exiting IRC::run
Sending SOPs:

***** ENDING THREAD ActionGlobalMinimize
***** STARTING THREAD ActionIdealize
***** ENDING THREAD ActionIdealize
***** STARTING THREAD ActionGlobalMinimize
Entering IRC::run
***** ENDING THREAD ActionGlobalMinimize
***** STARTING THREAD ActionIdealize
***** ENDING THREAD ActionIdealize
***** STARTING THREAD ActionGlobalMinimize
***** ENDING THREAD ActionGlobalMinimize

frood66's picture
User offline. Last seen 6 hours 10 min ago. Offline
Joined: 09/20/2011
Groups: Marvin's bunch
FWIW - this is only playable

FWIW - this is only playable for me because I'm using an old client - unplayable on current

bkoep's picture
User offline. Last seen 57 min 14 sec ago. Offline
Joined: 11/15/2012
Groups: None
Main or Devprev?

We're aware of some crashing problems with the current devprev version. Did you also have problems playing this on the current version of the "main" update group?

frood66's picture
User offline. Last seen 6 hours 10 min ago. Offline
Joined: 09/20/2011
Groups: Marvin's bunch
apologies - yes I am on main.

apologies - yes I am on main. I would not be but for the fact there are now issues with editing options.txt. (for mac anyhow)

I can go further - current main is very slow indeed - chat is a disaster area. SO I'll stick to this old main client for now.

actiasluna's picture
User offline. Last seen 10 hours 58 min ago. Offline
Joined: 03/05/2015
Groups: Gargleblasters
Can confirm 1278 crashes on main after latest

and submitted feedback and a crash log with info.
20160901-5afd216aff-osx_x86 is the main build I'm running.

Joined: 06/06/2013
Groups: Gargleblasters
chat crashing no matter what

I never took update and stayed on main. my IRC chat mysteriously disconnects at seeming random times (mibbit, which Bertro set up for me). My in game chat never stays connected, so I only use it to share pictures
All I can say is no one take it personally :)

toshiue's picture
User offline. Last seen 8 hours 24 min ago. Offline
Joined: 01/31/2016
Groups: Go Science
crashing constantly

am on main, crashing as frequently as every 10 minutes, regardless of action. completely un-playable, have not successfully completed any sequence since the crashes began. has been going on for about 16 hours now, since most recent update. am running Win 7, same end of log file as bertro posted, and am getting clusters of such in log file...

***** STARTING THREAD ActionLocalMinimize
core.optimization.LineMinimizer: Inaccurate G! step= 3.8147e-08 Deriv= -0.0834082 Finite Diff= 1.49767e+06
core.optimization.LineMinimizer: Inaccurate G! step= 9.53674e-09 Deriv= -0.0834082 Finite Diff= 5.99068e+06
core.optimization.LineMinimizer: Inaccurate G! step= 2.38419e-09 Deriv= -0.0834082 Finite Diff= 2.39627e+07
core.optimization.LineMinimizer: Inaccurate G! step= 5.96046e-10 Deriv= -0.0834082 Finite Diff= 9.58508e+07
core.optimization.LineMinimizer: Inaccurate G! step= 1.49012e-10 Deriv= -0.0834082 Finite Diff= 3.83403e+08
core.optimization.LineMinimizer: Inaccurate G! step= 3.72529e-11 Deriv= -0.0834082 Finite Diff= 1.53361e+09
core.optimization.LineMinimizer: Inaccurate G! step= 9.31323e-12 Deriv= -0.0834082 Finite Diff= 6.13445e+09
core.optimization.LineMinimizer: Inaccurate G! step= 2.32831e-12 Deriv= -0.0834082 Finite Diff= 2.45378e+10
core.optimization.LineMinimizer: Inaccurate G! step= 5.82077e-13 Deriv= -0.0834082 Finite Diff= 9.81513e+10
delta_score: -2.21917e-10
Playing sound: 4
***** ENDING THREAD ActionLocalMinimize
Tool on_action_complete called
delta_score: 0
Playing sound: 4
Tool on_action_complete called
***** STARTING THREAD ActionGlobalMinimize
core.optimization.LineMinimizer: Inaccurate G! step= 3.8147e-08 Deriv= -1.60528 Finite Diff= 1.49767e+06
core.optimization.LineMinimizer: Inaccurate G! step= 9.53674e-09 Deriv= -1.60528 Finite Diff= 5.99068e+06
core.optimization.LineMinimizer: Inaccurate G! step= 2.38419e-09 Deriv= -1.60528 Finite Diff= 2.39627e+07
core.optimization.LineMinimizer: Inaccurate G! step= 5.96046e-10 Deriv= -1.60528 Finite Diff= 9.58508e+07
core.optimization.LineMinimizer: Inaccurate G! step= 1.49012e-10 Deriv= -1.60528 Finite Diff= 3.83403e+08
core.optimization.LineMinimizer: Inaccurate G! step= 3.72529e-11 Deriv= -1.60528 Finite Diff= 1.53361e+09
core.optimization.LineMinimizer: Inaccurate G! step= 9.31323e-12 Deriv= -1.60528 Finite Diff= 6.13445e+09
core.optimization.LineMinimizer: Inaccurate G! step= 2.32831e-12 Deriv= -1.60528 Finite Diff= 2.45378e+10
core.optimization.LineMinimizer: Inaccurate G! step= 5.82077e-13 Deriv= -1.60528 Finite Diff= 9.81513e+10
core.optimization.LineMinimizer: Inaccurate G! step= 1.45519e-13 Deriv= -1.60528 Finite Diff= 3.92605e+11
core.optimization.LineMinimizer: Inaccurate G! step= 3.63798e-14 Deriv= -1.60528 Finite Diff= 1.57042e+12
Sending SOPs:

delta_score: 0
Playing sound: 4
***** ENDING THREAD ActionGlobalMinimize
Tool on_action_complete called
***** STARTING THREAD ActionLocalMinimize
core.optimization.LineMinimizer: Inaccurate G! step= 3.8147e-08 Deriv= -0.0834082 Finite Diff= 1.49767e+06
core.optimization.LineMinimizer: Inaccurate G! step= 9.53674e-09 Deriv= -0.0834082 Finite Diff= 5.99068e+06
core.optimization.LineMinimizer: Inaccurate G! step= 2.38419e-09 Deriv= -0.0834082 Finite Diff= 2.39627e+07
core.optimization.LineMinimizer: Inaccurate G! step= 5.96046e-10 Deriv= -0.0834082 Finite Diff= 9.58508e+07
core.optimization.LineMinimizer: Inaccurate G! step= 1.49012e-10 Deriv= -0.0834082 Finite Diff= 3.83403e+08
core.optimization.LineMinimizer: Inaccurate G! step= 3.72529e-11 Deriv= -0.0834082 Finite Diff= 1.53361e+09
core.optimization.LineMinimizer: Inaccurate G! step= 9.31323e-12 Deriv= -0.0834082 Finite Diff= 6.13445e+09
core.optimization.LineMinimizer: Inaccurate G! step= 2.32831e-12 Deriv= -0.0834082 Finite Diff= 2.45378e+10
core.optimization.LineMinimizer: Inaccurate G! step= 5.82077e-13 Deriv= -0.0834082 Finite Diff= 9.81513e+10
core.optimization.LineMinimizer: Inaccurate G! step= 1.45519e-13 Deriv= -0.0834082 Finite Diff= 106.25
core.optimization.LineMinimizer: Inaccurate G! step= 3.63798e-14 Deriv= -0.0834082 Finite Diff= 160.156
delta_score: 1.40062e-10
Playing sound: 4
***** ENDING THREAD ActionLocalMinimize

toshiue's picture
User offline. Last seen 8 hours 24 min ago. Offline
Joined: 01/31/2016
Groups: Go Science
re irc

forgot to say, rarely if ever us irc, but haven't seen any group/veteran/general irc traffic posted since the update...

mirp's picture
User offline. Last seen 46 weeks 4 days ago. Offline
Joined: 07/24/2012
Groups: Go Science
Unplayable.

Unplayable.

toshiue's picture
User offline. Last seen 8 hours 24 min ago. Offline
Joined: 01/31/2016
Groups: Go Science
unplayable

ditto mirp...

toshiue's picture
User offline. Last seen 8 hours 24 min ago. Offline
Joined: 01/31/2016
Groups: Go Science
still crashing...

gave it one last go with 6 hours left, crashed after 32 minutes...

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons