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1257: 65 Residue Monomer Design: Ideal Loop Filter
Status: Closed
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Evolvers
1 | Bletchley Park 9 8 | Contenders | 10,200 | 100 | 2 | mimi 46 1295 | Contenders | 10,176 | 98 | 3 | TomTaylor 46 1295 | Contenders | 10,154 | 95 | 4 | gitwut 46 1295 | Contenders | 10,146 | 92 | 5 | Galaxie 1 2 | Anthropic Dreams | 10,122 | 89 | 6 | lamoille 46 1295 | Anthropic Dreams | 10,120 | 86 | 7 | gdnskye 46 1295 | Anthropic Dreams | 10,117 | 84 | 8 | tokens 46 1295 | Anthropic Dreams | 10,114 | 81 | 9 | alwen 46 1295 | Anthropic Dreams | 10,107 | 78 | 10 | reefyrob 46 1295 | Beta Folders | 10,099 | 76 | 11 | LociOiling 2 1 | Beta Folders | 10,098 | 74 | 12 | smilingone 46 1295 | Beta Folders | 10,091 | 71 | 13 | Paulo Roque 46 1295 | Go Science | 10,065 | 69 | 14 | Bruno Kestemont 3 3 | Go Science | 10,064 | 67 | 15 | Hollinas 46 1295 | Go Science | 10,060 | 65 | 16 | Anfinsen_slept_here 15 38 | Go Science | 10,058 | 63 | 17 | Blipperman 34 42 | Gargleblasters | 10,033 | 61 | 18 | phi16 11 32 | Anthropic Dreams | 10,029 | 59 | 19 | Skippysk8s 33 40 | Gargleblasters | 10,026 | 57 | 20 | Mike Lewis 46 1295 | Gargleblasters | 10,023 | 55 | 21 | smholst 46 1295 | Gargleblasters | 10,021 | 53 | 22 | ManVsYard 46 1003 | Gargleblasters | 10,018 | 51 | 23 | hansvandenhof 46 477 | Anthropic Dreams | 10,009 | 49 | 24 | Cyberkashi 14 96 | Go Science | 10,006 | 48 | 25 | Scopper 46 1295 | Go Science | 9,907 | 46 | Need this puzzle? Log in to download.
Comments
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.
Residue Count: Penalizes extra residues inserted beyond the 65 residue limit. Players may insert up to 10 extra residues.
Ideal Loops: Penalizes loops that do not conform to preferred ABEGO patterns. Use Auto Structures to see which residues count as "loops."