puzzle picture
1236: 80 Residue Monomer Design: Residue Count Filter
Status: Closed


Name: 1236: 80 Residue Monomer Design: Residue Count Filter
Status: Closed
Created: 05/19/2016
Points: 100
Expired: 05/26/2016 - 23:00
Difficulty: Intermediate
Description: This design puzzle features a new filter: the Residue Count filter incurs a penalty when a player inserts extra residues beyond the 80 residue limit. The filter is intended to give players the flexibility to temporarily add residues to a design-in-progress. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!
Categories: Design, Overall

Top Groups

2Go Science10,57371
3Beta Folders10,49849
4Anthropic Dreams10,48333
5Void Crushers10,40022

Top Evolvers

Top Soloists

Need this puzzle? Log in to download.  


bkoep's picture
User offline. Last seen 34 min 52 sec ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.

Residue Count: Penalizes extra residues inserted beyond the 80 residue limit. Players may insert up to 10 extra residues.

Joined: 12/27/2012
contact bonus calculation

Contacts earn a weighted bonus. The formula for a made contact's bonus is:

bonus = 50 * contactmap.GetHeat ( xx, yy )

where xx and yy are the in-contact segments.

User login
Download links:
  Windows    OSX    Linux  
(10.12 or later)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Social Media

Only search fold.it
Other Games: Mozak
Recommend Foldit
Top New Users

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons