puzzle picture
1233: 90 Residue Monomer Design: Residue Count Filter
Status: Closed

Soloists

RankPlayerGroupScorePoints
126Cerzax 78 1451  7,3041
127cnhrcolemam 78 1451  7,0971
128penteplayer 78 1451 Go Science7,0821
129pandapharmd 78 725  7,0621
130DizzyMidget 78 1451  7,0331
131Abrolhos 78 1451  6,9101
132louiP 78 1451  6,8881
133rezaefar 78 108  6,7661
134cherry39 78 1451  6,7601
135favoritefightin... 78 1451  6,7501
136manasa 78 509 Go Science6,7421
137isantheautumn 78 1451  6,5541
138poiuyqwert 78 1451  6,5371
139bwkittitas 78 1451  5,9781
14001010011111 78 271 Go Science5,2731
141SKAT1990 78 1451  5,0441
142sean4046 78 1451  2,0651
143Ref_Jo 78 257  1,4431
144Watertop 78 1451  1,3341
145zkm 78 1451  1,3131
146Stephen R 78 1451  01
147larry25427 78 277  01
148jungenkind 78 1451  01
149Merlin43210 78 1451  01
150noforgiven 78 1451  01


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bkoep's picture
User offline. Last seen 14 hours 9 min ago. Offline
Joined: 11/15/2012
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Filters

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.

Residue Count: Penalizes extra residues inserted beyond the 90 residue limit. Players may insert up to 10 extra residues.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons