1202: 75 Residue Monomer Design

Summary

Name:

Status:

Closed

Created:

03/04/2016

Points:

100

Expired:

03/10/2016 - 23:00

Difficulty:

Intermediate

Description:

This is a basic 75 residue design puzzle with slightly up-weighted ideality scoring. Players should take care that all cutpoints are closed with good geometry! See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Categories:

Design, Overall

Rank

Group

Score

Points

Void Crushers

10,405

100

10,394

10,386

10,385

10,381

Rank

Player

Group

Score

Points

Mike Cassidy 59 30

Void Crushers

10,405

100

10,394

10,389

10,387

10,386

Rank

Player

Group

Score

Points

Timo van&n... 78 20

Void Crushers

10,403

100

10,385

10,376

10,367

10,362

Fri, 03/04/2016 - 00:06

bkoep 78 593

Offline

Joined: 11/15/2012

Groups: None

Filters

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.

Fri, 03/04/2016 - 19:56

Skippysk8s 14 15

Offline

Joined: 06/06/2013

Groups: Gargleblasters

can we list total points for filters please

Often during set up I may ignore some filters. It would be handy to post total filter points once I am ready to move from hand folding to recipes, as many ask for total filter score. I have been guessing...
Thanks