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1193: UMich Challenge: Refined Density
Status: Closed

Summary

Name: 1193: UMich Challenge: Refined Density
Status: Closed
Created: 02/11/2016
Points: 100
Expired: 02/19/2016 - 01:00
Difficulty: Intermediate
Description: This puzzle is a followup to Puzzle 1152: Foldit vs. UMich Electron Density Challenge. We were impressed with many players' solutions, and our UMich collaborators have a shared a higher resolution dataset of the same protein. Foldit solutions were used to develop a higher quality electron density map from the new dataset, and we’d like to see if players can use it to further improve this model! Pay special attention to residues 20-32 and 51-64, which were unresolved in Puzzle 1152. Note that players will not be able to load in solutions from Puzzle 1152.
Categories: Electron Density, Overall, Prediction

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RankGroupScorePoints
1Anthropic Dreams30,107100
2Void Crushers30,06580
3Contenders30,02063
4Go Science30,01349
5Beta Folders30,00637

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Comments

Joined: 03/30/2013
Groups: Go Science
I would like to know

I would like to know something about the model we have been given. And I suspect i am not alone.
Can you tell us what the resolution is on the ED map?

I am also curious about the R factor. Is it below 30%? Below 25%? (I confess to being a nerd, and a once-upon-a-time crystallographer.) But i think the community could benefit from some notion of how good the model is, and where we are in the process.)

Thanks.

bkoep's picture
User offline. Last seen 14 hours 56 min ago. Offline
Joined: 11/15/2012
Groups: None
Good questions!

The resolution of this dataset is 1.8 Å.

The R factor is below 30%, so the starting model is pretty close to the correct structure.

Susume's picture
User offline. Last seen 22 hours 43 min ago. Offline
Joined: 10/02/2011
Who we're competing with

bkoep mentioned this in chat: "Ah, actually, the UMich students are not involved in this challenge. I forgot to mention that in the puzzle description. For this puzzle, we're more interested in how Foldit solutions compare to those of expert crystallographers."

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons