puzzle picture
1160: 70 Residue Monomer Design
Status: Closed

Summary

Name: 1160: 70 Residue Monomer Design
Status: Closed
Created: 11/20/2015
Points: 100
Expired: 11/27/2015 - 23:00
Difficulty: Intermediate
Description: This is a basic 70 residue design puzzle without any Fragment Filter. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!
Categories: Design, Overall

Top Groups

RankGroupScorePoints
1Go Science10,421100
2Gargleblasters10,40379
3Beta Folders10,39061
4Anthropic Dreams10,34147
5L'Alliance Francophone10,32735

Top Evolvers

Top Soloists



Need this puzzle? Log in to download.  

Comments

bkoep's picture
User offline. Last seen 3 hours 52 min ago. Offline
Joined: 11/15/2012
Groups: None
Filters

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.

Joined: 04/11/2013
Mutate No Wiggle

I would and probably others would highly appreciate it if there was someone who would not mind modifying mutate no wiggle from brow to recognise the criteria for the secondary structure design.

It would save a lot of time having to go back and allow GLY, ALA and PRO in loops.

lotsa luv

Porky (soon to be parky)

:)

Get Started: Download
  Windows    OSX    Linux  
Windows
(7/8/10)
OSX
(10.7 or later)
Linux
(64-bit)

Are you new to Foldit? Click here.

Are you a student? Click here.

Are you an educator? Click here.
Search
Only search fold.it
Recommend Foldit
User login
Soloists
Evolvers
Groups
Topics
Top New Users
Sitemap

Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons