Fri, 08/21/2015 - 20:21
#2
scores and bonding seem to be
scores and bonding seem to be elusive in the same structure
Mon, 08/24/2015 - 14:27
#3
shared a couple with
shared a couple with scientists, might help figure out the scoring issue
best is 355 hbond 12500 on total with -300 on the complex score
Wed, 08/26/2015 - 23:11
#4
Thanks retiredmichael!
I'll take a look.
Wed, 08/26/2015 - 23:31
#5
More interfase
Is it posible to get a puzzle with a more stringent interfase requirement? For example a dimer with Core Complex- 2 Core Monomer > 14-17 segments 20%-25% of the total size (70 on this one)
Or even better a trimmer with Core Complex- 3 Core Monomer > 14-17 segments 20%-25% of the total size (70 on this one)
Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
HBond Network: Rewards networks comprising at least three hydrogen bonds, with at least one hydrogen bond spanning the dimer interface. In addition, at least 75% of all polar atoms in the network must make hydrogen bonds.
Core Existence: Monomer: Ensures that at least 21 residues are buried in the core of the monomer unit.
Core Existence: Complex: Ensures that at least 48 residues are buried in the core of the entire complex (including the interface between monomer units).
Fragment Score: Scans for parts of your design that are unlikely to fold up naturally. Use Rebuild and Remix tools to fix these regions of your design!