puzzle picture
1079: Blind Electron Density 11
Status: Closed

Summary

Name: 1079: Blind Electron Density 11
Status: Closed
Created: 04/23/2015
Points: 100
Expired: 04/30/2015 - 23:00
Difficulty: Intermediate
Description: This protein was designed in the Baker Lab, but we've had a lot of difficulty solving its crystal structure! Use all your Electron Density folding skills to fit the density as well as you can.
Categories: Electron Density, Overall, Prediction

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RankGroupScorePoints
1Anthropic Dreams13,906100
2Contenders13,90379
3Beta Folders13,89961
4Russian team13,85047
5Void Crushers13,84835

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Comments

Susume's picture
User offline. Last seen 5 days 3 hours ago. Offline
Joined: 10/02/2011
design

Awesome design! I'm jealous.

Joined: 08/24/2011
Groups: Go Science
Polymer?

Is it just me, or does the ED data make it look like this monomer is part of some kind of giant polymer barrel?

Joined: 08/24/2011
Groups: Go Science
And by polymer I mean

And by polymer I mean oligomer.

bkoep's picture
User offline. Last seen 2 days 3 hours ago. Offline
Joined: 11/15/2012
Groups: None
Yes!

Interestingly enough, this protein does crystallize such that four monomers arrange into a kind of beta-barrel. However, the protein is monomeric in solution.

Joined: 03/27/2015
Groups: Gargleblasters
it's just you

it's just you

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons