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1067: Unsolved VEGF protein: Domain 1
Status: Closed

Summary

Name: 1067: Unsolved VEGF protein: Domain 1
Status: Closed
Created: 03/18/2015
Points: 100
Expired: 04/03/2015 - 09:00
Difficulty: Intermediate
Description: The first two puzzles for this protein were able to significantly improve the structure of domain 6 of this protein, so we are giving you a different domain this time, with 5 Zhang Server predictions as starting points. Resetting the puzzle will cycle through each model. We are giving you 2 weeks to work on this puzzle, so please try out each server start. Although one server model scores better than the rest initially, it might be the furthest from the native and might not get you the most points in the end! More info in the puzzle comments.
Categories: Overall, Prediction

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Comments

beta_helix's picture
User offline. Last seen 1 day 16 hours ago. Offline
Joined: 05/09/2008
Groups: None
Additional information:

Please read the updated blog entry about this unsolved protein.
________________

The SAM server is still down, so here are the secondary structure predictions that were used for the starting chain:

The higher the number, the higher the confidence of the secondary structure prediction above it.
________________

Here is the link to the Zhang Server website (where you can find a lot more detailed info such as templates used and predicted per-residue accuracy for each model):
http://zhanglab.ccmb.med.umich.edu/I-TASSER/output/S218744

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons