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1043: 55 Residue Symmetric Hexamer Design
Status: Closed

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bkoep's picture
User offline. Last seen 54 min 12 sec ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Monomer: Ensures that at least 20% of the residues are buried in the core of the monomer unit.

Core Existence: Complex: Ensures that at least 35% of the residues are buried in the core of the entire complex (including the interface between monomer units).

Fragment Score: Scans for parts of your design that are unlikely to fold up naturally. Use Rebuild and Remix tools to fix these regions of your design!

Secondary Structure Design: Penalizes GLY, ALA, and PRO residues in helices and sheets.

alwen's picture
User offline. Last seen 17 min 57 sec ago. Offline
Joined: 10/03/2011
Folding this one is like

Folding this one is like pushing a tank with my forehead.

Stopping a wiggle takes 20 seconds. I timed it! Twenty seconds from clicking Stop to actually stopping.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, RosettaCommons