bkoep's picture
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Monomer: Ensures that at least 20% of the residues are buried in the core of the monomer unit.

Core Existence: Complex: Ensures that at least 35% of the residues are buried in the core of the entire complex (including the interface between monomer units).

Fragment Score: Scans for parts of your design that are unlikely to fold up naturally. Use Rebuild and Remix tools to fix these regions of your design!

Secondary Structure Design: Penalizes GLY, ALA, and PRO residues in helices and sheets.

spmm's picture
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scores seem low on this?

https://fold.it/portal/node/998143 - a recent 65 res monomer design scored 10,800 - the scoreboards are red for the top ten as well.

bkoep's picture
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I don't think so

In general, Foldit score does increase with the number of residues in a design, but "symmetric residues" do not contribute in this case. We expect designs in this puzzle to score similarly to a 50 residue monomer, with the addition of the interface points for a single monomer subunit.

spmm's picture
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thanks

so multiplying by 5 was a tad simplistic, good to know

Joined: 09/24/2012
Groups: Go Science
I made statistics 1-2 years ago

I found the formula was like 8000 + net filters+ about [13-25] * monomer number of residues * symmetry

That would make a potential of about
11720 to 14720 pts for this one

11523 seems quite low indeed, but I think it's much more difficult to get higher scores with the many conditions that are present now.

(In the past, you had more freedom to find unrealistic high scoring solutions).

paviraj's picture
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thanks

so multiplying by 5 was a tad simplistic, good to know

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