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1033: 80 Residue Monomer Design: Zero Cysteines
Status: Closed
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Groups
1 | Anthropic Dreams | 10,584 | 100 | 2 | Go Science | 10,433 | 82 | 3 | Another Hour Another Point | 10,420 | 66 | 4 | Beta Folders | 10,399 | 53 | 5 | Void Crushers | 10,321 | 42 | 6 | L'Alliance Francophone | 10,293 | 33 | 7 | An Art That's Smart | 10,221 | 26 | 8 | Contenders | 10,205 | 20 | 9 | FoldIt@Netherlands | 10,154 | 15 | 10 | Gargleblasters | 10,088 | 11 | 11 | Hun-Magyar Csapat | 9,638 | 8 | 12 | Italiani Al Lavoro | 9,575 | 6 | 13 | Repro-men | 9,147 | 4 | 14 | Herobrine's Army | 8,901 | 3 | 15 | xkcd | 8,530 | 2 | 16 | E?????! Heureka! | 7,847 | 2 | 17 | freefolder | 7,742 | 1 | 18 | Natural Abilities | 7,439 | 1 | 19 | Russian team | 7,374 | 1 | 20 | 0science0 | 7,284 | 1 | 21 | DSN @ Home | 7,021 | 1 | 22 | HYSA_STEM | 2,747 | 1 | 23 | Waverki | 0 | 1 | 24 | uneRx | 0 | 1 | 25 | Richard Dawkins Foundation | 0 | 1 | Need this puzzle? Log in to download.
Comments
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Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.
Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.
Fragment Score: Scans for parts of your design that are unlikely to fold up naturally. Use Rebuild and Remix tools to fix these regions of your design!
Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.
Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets. Also penalizes hydrophilic residues in the core and hydrophobic residues on the surface.