puzzle picture
1032: De-novo Freestyle 46: Hand-folding Round
Status: Closed


Name: 1032: De-novo Freestyle 46: Hand-folding Round
Status: Closed
Created: 01/05/2015
Points: 100
Expired: 01/12/2015 - 23:00
Difficulty: Intermediate
Description: It's been a while since our last hand-folding challenge! In this de-novo freestyle puzzle, only GUI scripts are allowed and sharing has been disabled. After this puzzle expires, the puzzle will be reposted with LUA scripts and sharing enabled. The secondary structure predictions are provided on the starting model, with more details posted in the puzzle comments.
Categories: Hand-Folding, Overall, Prediction

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2Beta Folders9,33781
3 An Art That's Smart9,25364
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bkoep's picture
User offline. Last seen 4 hours 46 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
Secondary structure predictions coming soon!

SS predictions from the SAM server are forthcoming, so check back soon. The starting model shows secondary structure as predicted by PSIPRED.

bkoep's picture
User offline. Last seen 4 hours 46 min ago. Offline
Joined: 11/15/2012
Groups: Foldit Staff
SAM secondary structure predictions

Here is the sequence logo predicted by the SAM server:

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

Joined: 06/06/2013
Groups: Gargleblasters
Eek! a little big for first try at hand folding

I don't seem to have any SS predictions....or any idea what to do given some of these sequences. We need a hand fold puzzle for first timers. Totally lost

Joined: 06/06/2013
Groups: Gargleblasters
found SS when reset puzzle

there was NO SS the first time I opened this. a little overwhelming and large for a novice... Still would like a first timer only puzzle for those of us who have never hand folded. A little smaller to be managable

Joined: 09/24/2012
Groups: Go Science

is on the screen, but you wont see beautifull helixes.
Use Ideal SS tool or rebuild to form nice helixes. Then cut, move, uncut as you like to imagine a beautifull TS
There are some video to show how to do from here:

Joined: 07/21/2013
Groups: Beta Folders
can I share this?

I tried to share a version of this puzzles with my group. I could not. I noticed that there is no other shared versions of this puzzle for my group. There is no "Top evolvers" for this puzzle.

Joined: 09/24/2012
Groups: Go Science

Hand folding round allows no sharing.
There will be a second round with scripts and sharing allowed.
If you want, you can share a picture to your group trough group chat.

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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
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