The rundown on coronavirus

You don't have to be a scientist to do science! Download and play Foldit and you can help researchers discover new antiviral drugs that might stop coronavirus! The most promising solutions will be manufactured and tested at the University of Washington Institute for Protein Design in Seattle.

Foldit is run by academic research scientists. It is free to play and not-for-profit. To get started, download Foldit and create a username!

We recommend that new players start with the Foldit Intro Puzzles.
After some practice, move on to the Science Puzzles and try out the Beginner: Coronavirus puzzle.
We also have an advanced puzzle NEW advanced puzzle where you can try to design an antiviral protein from scratch!

To meet other players, check out the Foldit Discord channels.

Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate idle CPU cycles to science, please check out the Rosetta@Home project on BOINC.

(Wed, 03/04/2020 - 05:46  |  10 comments)

A Reminder of the Community Rules

Hello all! Hope you are enjoying this fine Tuesday. I wanted to take a brief moment to remind everyone about the Foldit Community Rules. As part of the community, everyone is expected to adhere to these rules at all times, so it is important all are aware of what is expected. Here are the highlights:

  • Keep the conversation PG-rated, since there is a wide range of ages in the community. Anything deemed offensive or obscene will not be tolerated.
(Tue, 06/20/2017 - 22:30  |  1 comment)

Developer Preview Release Soon

Hey everyone,

We're about to push a big update to the developer preview soon with additions and changes to Foldit Small Molecule Design. You can read more about this exciting new mode here. Read below for a full list of the changes:

* A major overhaul and update to the Small Molecule Design tool.
* Two new tutorials demonstrating how to use Small Molecule Design.
* A new "Binding Site" option in the "View Protein" section of the View Options -- this is like Cartoon Ligand, but hides parts of the protein which are far from the ligand.

(Wed, 10/13/2021 - 01:52  |  3 comments)

New Release

Hey all,

We've just released an update to the Foldit client with the following fixes and changes:

General:
* Updated the help panel.
* Scaled opengl view for high-resolution displays.
* Added an orthographic view option.
* Added structure.IsLockedAll() Lua function.
* The Pick Sidechains tool now selects among buried rotamers.

Localization:
* Added a pseudolocalization language to allow translators to see all translatable strings.
* Update the description for Korean in localization.

Bug Fixes:
* Prevent crash on filter.GetData when no data.

(Fri, 10/08/2021 - 15:05  |  0 comments)

Newsletters!

Missed the latest newsletters? Be sure to check them out here! Click this link to sign-up to get news and information each Friday!

(Tue, 10/05/2021 - 03:09  |  0 comments)

Lab Report #25: Education Mode

Foldit Education Mode spells out the science of proteins. Built for students, teachers, and you!

NEWS
- Education Mode now available from the Foldit puzzle menu

PUZZLE UPDATES
- Protein binder design for TGF-beta, IL-2 receptor, CD47
- Symmetric design puzzles

DESIGN OF THE MONTH

(Fri, 10/01/2021 - 13:02  |  1 comment)

Temporary server issues

We are currently experiencing a problem with our server that will prevent users from signing from the Foldit application or playing Foldit online.

Update: Everyone should now have normally functioning connections to the server again. Thanks for your patience!

(Thu, 09/30/2021 - 17:12  |  15 comments)

Developer Preview Release Soon

Hey all,

We are about to push an update to the developer preview with the following fixes and features:

General:
* Updated the help panel.
* Scaled opengl view for high-resolution displays.
* Added an orthographic view option.
* Added structure.IsLockedAll() Lua function.
* The Pick Sidechains tool now selects among buried rotamers.

Localization:
* Added a pseudolocalization language to allow translators to see all translatable strings.
* Update the description for Korean in localization.

Bug Fixes:
* Prevent crash on filter.GetData when no data.

(Tue, 09/28/2021 - 14:58  |  2 comments)

Office hour 9/17/21

Hey folks! We're going to be doing an Office Hour this Friday, 9/17 at 3 PM ET (Time Zone Converter). It will be led by beta_helix this time around. Come join us to chat about Electron Density--this is also an awesome opportunity to meet new Foldit Developer apetrides and discuss new ED tools (such as the new Select Cloud feature in Devprev).

(Thu, 09/16/2021 - 20:04  |  0 comments)

Developer Preview Release Soon

Hey everyone,

We're about to push an update to the developer preview with some fixes and changes:

General:
* The Deepmind Alphafold panel has been redesigned!
* You can now select the residues that fall within the visible sphere from the electron density panel.

Additionally, we have changed some things under the hood that shouldn't have an effect on the player experience, but let us know if you see anything odd.

(Tue, 09/14/2021 - 23:17  |  3 comments)
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Developed by: UW Center for Game Science, UW Institute for Protein Design, Northeastern University, Vanderbilt University Meiler Lab, UC Davis
Supported by: DARPA, NSF, NIH, HHMI, Amazon, Microsoft, Adobe, Boehringer Ingelheim, RosettaCommons