New AlphaFold blog post!
AlphaFold, which was developed by DeepMind in 2018, uses a sophisticated machine-learning algorithm to derive structural information from a protein's sequence. In the last CASP competition, it out-performed every other method for protein structure prediction! In this latest blog post, we take a look at the AlphaFold method and its impact on protein research!(Fri, 01/31/2020 - 00:57 | 3 comments)
Now hiring at the Institute for Protein Design!
The UW Institute for Protein Design is hiring for a research assistant position in Seattle, WA! This position is specifically to help with the crystallization of proteins designed by Foldit players and others at the Institute!
Protein designers rely on crystallization and x-ray diffraction experiments to determine if their proteins fold correctly. If these kinds of experiments interest you, we want your help crystallizing more proteins at the Institute! No experience with protein crystallography is necessary.
Apply now through the UW Hires portal!(Wed, 01/29/2020 - 00:45 | 1 comment)
Foldit Lab Report #4: 1,994 genes!
Happy New Year! Watch Foldit Lab Report #4 on YouTube now!
- Science Chat recap
- New electron density puzzles (crystals, not cryo)
- We're trying to make poly-proline easier, we promise
- Can you make a Baker lab design even better?
- More and more and more symmetry
DESIGN OF THE MONTH
- fiendish_ghoul designed a scary good hydrogen-bonded trimer.
- Some of your dimers appear to be working...
- We'll soon be testing almost 2,000 Foldit player designs! We've never been able to generate this much data before. Stay tuned to hear what we learn.
Winter Science Chat
Just a friendly reminder that our science chat will be happening tomorrow at 12:30 PM PST; 8:30 GMT in #veterans chat. Hope to see you there!(Tue, 12/03/2019 - 02:01 | 6 comments)
Foldit Lab Report #3: We Got a Paper
Check out Foldit Lab Report #3 on YouTube now! As always, please leave a comment to let us know what you want to see next time!
- Foldit players have contributed to another scientific paper!
- Check out the blog to learn more.
- Upcoming Science Chat: December 3, 2019
- neilpg628 introduces the poly-proline helix.
- De novo freestyle puzzles challenge you to predict another player's structure.
- Hydrogen bond networks have returned to make symmetric design easier.
DESIGN OF THE MONTH
- spvincent has created a monstrous hydrogen-bonded trimer.
- About 30 of your designs are being tested at the moment.
- Want to see what making proteins looks like? Let us know!
- We are not changing any player privacy settings.